In vitro and in silico studies of a Zn(II) complex as a potential therapeutic agent for breast cancer

In vitro and in silico studies of a Zn(II) complex as a potential therapeutic agent for breast cancer

Abstract Breast cancer (BC) is one of the most life-threatening diseases of women’s health worldwide. This work was conducted to assess the anti-BC potency of a new Zn(II)-based complex. The Zn(II) complex coordinated to dimethoxy-substituted bipyridine was synthesized and its molecular structure wa...

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Bibliographic Details
Main Authors: Marzieh Anjomshoa, Bagher Amirheidari, Jan Janczak, Mehdi Sahihi, Yasaman Abolhassani, Alireza Farsinejad, Hamid Forootanfar
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Subjects:
Zn(II) complex
4,4′-Dimethoxy-2,2′-bipyridine
Apoptosis
Anti-metastasis
ROS generation
Gene expression
Online Access:https://doi.org/10.1038/s41598-024-79644-0
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https://doi.org/10.1038/s41598-024-79644-0

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