Glycerophospholipid metabolism licenses IgE-mediated mast cell degranulation

Summary: Immunoglobulin E (IgE) antibodies and mast cells have been extensively recognized to dictate the pathophysiology of anaphylaxis and allergic reactions; nevertheless, the pivotal cues driving IgE-mediated mast cell degranulation remain enigmatic. Here, we demonstrate that FcεRI aggregation-i...

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Bibliographic Details
Main Authors: Yaoyao Xia, Peng Bin, Youyou Zhou, Muyang Zhao, Jianglin Zhang, Weiming Zhong, Na Wang, Bingfeng Wang, Wenkai Ren
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Cell Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2211124725005133
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