Ex Vivo Nicotine Stimulation Augments the Efficacy of Human Peripheral Blood Mononuclear Cell-Derived Dendritic Cell Vaccination via Activating Akt-S6 Pathway

Ex Vivo Nicotine Stimulation Augments the Efficacy of Human Peripheral Blood Mononuclear Cell-Derived Dendritic Cell Vaccination via Activating Akt-S6 Pathway

Our previous studies showed that α7 nicotinic acetylcholine receptor (nAchR) agonist nicotine has stimulatory effects on murine bone marrow-derived semimature DCs, but the effect of nicotine on peripheral blood mononuclear cell- (PBMC-) derived human semimature dendritic cells (hu-imDCs) is still to...

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Bibliographic Details
Main Authors: Yan Yan Wang, Yi Wen Yang, Xiang You, Xiao Qian Deng, Chun Fang Hu, Cong Zhu, Jun Yao Wang, Jiao Jiao Gu, Yi Nan Wang, Qing Li, Feng Guang Gao
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Analytical Cellular Pathology
Online Access:http://dx.doi.org/10.1155/2015/741487
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http://dx.doi.org/10.1155/2015/741487

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