AKT1-Mediated NOTCH1 phosphorylation promotes gastric cancer progression via targeted regulation of IRS-1 transcription
Abstract Purpose This study aimed to investigate that AKT1-Mediated NOTCH1 phosphorylation promotes gastric cancer (GC) progression via targeted regulation of IRS-1 transcription. Methods The study utilized databases such as PhosphositePlus, TRANSFAC, CHEA, GPS 5.0, and TCGA, along with experimental...
Saved in:
Main Authors: | Lingshan Zhou, Yuan Yang, Qian Qiao, Yingying Mi, Yuling Gan, Ya Zheng, Yuping Wang, Min Liu, Yongning Zhou |
---|---|
Format: | Article |
Language: | English |
Published: |
Springer
2024-12-01
|
Series: | Journal of Cancer Research and Clinical Oncology |
Subjects: | |
Online Access: | https://doi.org/10.1007/s00432-024-06039-z |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Frk positively regulates innate antiviral immunity by phosphorylating TBK1
by: Xiaomei Zhang, et al.
Published: (2025-02-01) -
The heterogeneity of NOTCH1 to tumor immune infiltration in pan-cancer
by: XiaoJun Duan, et al.
Published: (2024-11-01) -
ATF3 Knockdown Exacerbates Astrocyte Activation by Inhibiting Phosphorylation of Drp1 in Ischemic Stroke
by: Huang R, et al.
Published: (2025-02-01) -
Faith, hope and love - a missionary perspective on three seminal motifs in 1 Thessalonians 1:3
by: P. G. R. de Villiers
Published: (2003-06-01) -
Transcription factor RUNX1 regulates coagulation factor XIII-A (F13A1): decreased platelet-megakaryocyte F13A1 expression and clot contraction in RUNX1 haplodeficiency
by: Fabiola Del Carpio-Cano, et al.
Published: (2025-01-01)