AKT1-Mediated NOTCH1 phosphorylation promotes gastric cancer progression via targeted regulation of IRS-1 transcription
Abstract Purpose This study aimed to investigate that AKT1-Mediated NOTCH1 phosphorylation promotes gastric cancer (GC) progression via targeted regulation of IRS-1 transcription. Methods The study utilized databases such as PhosphositePlus, TRANSFAC, CHEA, GPS 5.0, and TCGA, along with experimental...
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Main Authors: | Lingshan Zhou, Yuan Yang, Qian Qiao, Yingying Mi, Yuling Gan, Ya Zheng, Yuping Wang, Min Liu, Yongning Zhou |
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Format: | Article |
Language: | English |
Published: |
Springer
2024-12-01
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Series: | Journal of Cancer Research and Clinical Oncology |
Subjects: | |
Online Access: | https://doi.org/10.1007/s00432-024-06039-z |
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