AKT1-Mediated NOTCH1 phosphorylation promotes gastric cancer progression via targeted regulation of IRS-1 transcription

AKT1-Mediated NOTCH1 phosphorylation promotes gastric cancer progression via targeted regulation of IRS-1 transcription

Abstract Purpose This study aimed to investigate that AKT1-Mediated NOTCH1 phosphorylation promotes gastric cancer (GC) progression via targeted regulation of IRS-1 transcription. Methods The study utilized databases such as PhosphositePlus, TRANSFAC, CHEA, GPS 5.0, and TCGA, along with experimental...

Full description

Saved in:
Bibliographic Details
Main Authors: Lingshan Zhou, Yuan Yang, Qian Qiao, Yingying Mi, Yuling Gan, Ya Zheng, Yuping Wang, Min Liu, Yongning Zhou
Format: Article
Language:English
Published: Springer 2024-12-01
Series:Journal of Cancer Research and Clinical Oncology
Subjects:
Gastric cancer
Notch1 phosphorylation
AKT1
IRS-1
Inhibition
Online Access:https://doi.org/10.1007/s00432-024-06039-z
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1007/s00432-024-06039-z

Similar Items