Oncogene-tumor suppressor gene feedback interactions and their control
We propose the hypothesis that for a particular type of cancer there exists a key pair of oncogene (OCG) and tumor suppressor gene (TSG) that is normally involved in strong stabilizing negative feedback loops (nFBLs) of molecular interactions, and it is these interactions that are sufficiently pertu...
Saved in:
Main Authors: | Baltazar D. Aguda, Ricardo C.H. del Rosario, Michael W.Y. Chan |
---|---|
Format: | Article |
Language: | English |
Published: |
AIMS Press
2015-07-01
|
Series: | Mathematical Biosciences and Engineering |
Subjects: | |
Online Access: | https://www.aimspress.com/article/doi/10.3934/mbe.2015.12.1277 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Oncogenic mutant KRAS inhibition through oxidation at cysteine 118
by: Maximilian Kramer‐Drauberg, et al.
Published: (2025-02-01) -
Impact of R-loops on oncogene-induced replication stress in cancer cells
by: Heuzé, Jonathan, et al.
Published: (2023-09-01) -
Ubiquitination Enzymes in Cancer, Cancer Immune Evasion, and Potential Therapeutic Opportunities
by: Aiman B. Awan, et al.
Published: (2025-01-01) -
ROLE OF HETEROZYGOUS TUMOR SUPPRESSORS IN THE LIFE LONGEVITY OF DROSOPHILA MELANOGASTER
by: S. A. Kopyl, et al.
Published: (2015-01-01) -
Multistability, oscillations and bifurcations in feedback loops
by: Maria Conceição A. Leite, et al.
Published: (2009-12-01)