Oncogene-tumor suppressor gene feedback interactions and their control

We propose the hypothesis that for a particular type of cancer there exists a key pair of oncogene (OCG) and tumor suppressor gene (TSG) that is normally involved in strong stabilizing negative feedback loops (nFBLs) of molecular interactions, and it is these interactions that are sufficiently pertu...

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Bibliographic Details
Main Authors: Baltazar D. Aguda, Ricardo C.H. del Rosario, Michael W.Y. Chan
Format: Article
Language:English
Published: AIMS Press 2015-07-01
Series:Mathematical Biosciences and Engineering
Subjects:
Online Access:https://www.aimspress.com/article/doi/10.3934/mbe.2015.12.1277
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