New Approach Methodologies (NAMs) to assess killer whale (Orcinus orca) estrogen receptor alpha (ERα) transactivation potencies by DDTs and their risks

New Approach Methodologies (NAMs) to assess killer whale (Orcinus orca) estrogen receptor alpha (ERα) transactivation potencies by DDTs and their risks

Killer whales (Orcinus orca), as apex predators, accumulate high levels of persistent organic pollutants (POPs) such as dichlorodiphenyltrichloroethane and its analogs (DDTs) and face their risks at the population level. The assessment of the function of estrogen receptor alpha (ERα) is crucial for...

Full description

Saved in:
Bibliographic Details
Main Authors: Dave Arthur R. Robledo, Takahito Kumagawa, Mari Ochiai, Hisato Iwata
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Killer whales
DDTs
Estrogen receptor α (ERα)
Endocrine disruption
New Approach Methodologies (NAMs)
Risk assessment
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651325000971
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items