An Outbreak of Hepatic Veno-Occlusive Disease in Western Afghanistan Associated with Exposure to Wheat Flour Contaminated with Pyrrolizidine Alkaloids

Pyrrolizidine alakloids (PAs) are known to cause hepatic veno-occlusive disease (VOD). Outbreaks have occurred in Western Afghanistan since 1974, the latest in February 2008. We conducted an outbreak investigation using a case-control design. Sixty-seven cases of VOD were compared with 199 community...

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Bibliographic Details
Main Authors: Faizullah Kakar, Zarif Akbarian, Toby Leslie, Mir Lais Mustafa, John Watson, Hans P. van Egmond, Mohammad Fahim Omar, Jawad Mofleh
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:Journal of Toxicology
Online Access:http://dx.doi.org/10.1155/2010/313280
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