Variation in Glucose-6-Phosphate Dehydrogenase activity following acute malaria.

Variation in Glucose-6-Phosphate Dehydrogenase activity following acute malaria.

Primaquine and tafenoquine are the only licensed drugs with activity against Plasmodium vivax hypnozoites but cause haemolysis in patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency. Malaria also causes haemolysis, leading to the replacement of older erythrocytes with low G6PD activity...

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Main Authors: Benedikt Ley, Mohammad Shafiul Alam, Ari Winasti Satyagraha, Ching Swe Phru, Kamala Thriemer, Dagimawie Tadesse, Tamiru Shibiru, Asrat Hailu, Mohammad Golam Kibria, Mohammad Sharif Hossain, Hisni Rahmat, Jeanne R Poespoprodjo, Wasif Ali Khan, Julie A Simpson, Ric N Price
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-05-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0010406&type=printable
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https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0010406&type=printable

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