Effectively simplified Adriamycin‐induced chronic kidney disease mouse model: Retro‐orbital vein injection versus tail‐vein injection

Effectively simplified Adriamycin‐induced chronic kidney disease mouse model: Retro‐orbital vein injection versus tail‐vein injection

Abstract This study aimed to investigate the impact of administration routes in establishing the Adriamycin (ADR)‐induced chronic kidney disease (CKD) model. Using BALB/c mice, we compared the effects of conventional tail‐vein injection (TV10, 10 mg/kg) to those of retro‐orbital sinus (orbital vein)...

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Bibliographic Details
Main Authors: Masaki Watanabe, Hayato R. Takimoto, Kazuki Hashimoto, Yuki Ishii, Nobuya Sasaki
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:Animal Models and Experimental Medicine
Subjects:
Adriamycin nephropathy
BALB/c
CKD
orbital vein injection
tail‐vein injection
Online Access:https://doi.org/10.1002/ame2.12553
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https://doi.org/10.1002/ame2.12553

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