Fluoxetine inhibited RANKL-induced osteoclastic differentiation in vitro

Fluoxetine inhibited RANKL-induced osteoclastic differentiation in vitro

Selective serotonin reuptake inhibitor correlates with decreased bone mineral density and impedes orthodontic tooth movement. The present study aimed to examine the effects of fluoxetine on osteoclast differentiation and function. Human peripheral blood mononuclear cells (hPBMCs) and murine RAW264.7...

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Bibliographic Details
Main Authors: Zhang Jing-wen, Zhao Fang-bing, Ma Bing’er, Shen Xiao-qing, Geng Yuan-ming
Format: Article
Language:English
Published: De Gruyter 2024-12-01
Series:Open Medicine
Subjects:
osteoclast
receptor activator of nuclear factor kappa-b ligand
selective serotonin reuptake inhibitor
fluoxetine
orthodontic tooth movement
Online Access:https://doi.org/10.1515/med-2024-1094
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https://doi.org/10.1515/med-2024-1094

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