Safinamide as an adjunct to levodopa monotherapy in Asian patients with Parkinson’s disease experiencing early wearing-off: a pooled analysis of the J-SILVER and KEEP studies

Safinamide as an adjunct to levodopa monotherapy in Asian patients with Parkinson’s disease experiencing early wearing-off: a pooled analysis of the J-SILVER and KEEP studies

BackgroundLimited trials are evaluating the efficacy of monoamine oxidase B inhibitors as an adjunct to levodopa monotherapy for early wearing-off in Parkinson’s disease (PD). We evaluated the efficacy and safety of safinamide in patients with fluctuating PD treated with levodopa monotherapy.Methods...

Full description

Saved in:
Bibliographic Details
Main Authors: Noriko Nishikawa, Do-Young Kwon, Yuki Kogo, Taku Hatano, Jin Whan Cho, Chizuru Kobayashi, Hiroyuki Shiiba, JiEun Kim, Takayuki Ishida, Jong Sam Baik, Nobutaka Hattori
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Neurology
Subjects:
Parkinson’s disease
MAO-B inhibitor
safinamide
sodium channel blocker
early wearing-off
elderly
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2025.1591664/full
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.frontiersin.org/articles/10.3389/fneur.2025.1591664/full

Similar Items