Circulating miR-134 in mesial temporal lobe epilepsy: implications in hippocampal sclerosis development and drug resistance

Circulating miR-134 in mesial temporal lobe epilepsy: implications in hippocampal sclerosis development and drug resistance

AimmiR-134 has been widely reported as upregulated in experimental and human studies of Mesial Temporal Lobe Epilepsy the most common drug-resistant epilepsy (DRE). Studies have shown that the use of antagomirs, anti-miR-134, may be a promising therapeutic approach to these epilepsies. However, data...

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Main Authors: Bárbara Guerra Leal, Cláudia Carvalho, Cristina Santos, Raquel Samões, Ricardo Martins-Ferreira, Catarina Teixeira, Diana Rodrigues, Joel Freitas, Carolina Lemos, Rui Chorão, João Ramalheira, João Lopes, António Martins da Silva, Paulo Pinho e Costa, João Chaves
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Molecular Neuroscience
Subjects:
MTLE
microRNAs
biomarkers
DRE
miR-134
GGE
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2024.1512860/full
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https://www.frontiersin.org/articles/10.3389/fnmol.2024.1512860/full

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