A narrative review of research advancements in pharmacogenetics of cardiovascular disease and impact on clinical implications

A narrative review of research advancements in pharmacogenetics of cardiovascular disease and impact on clinical implications

Abstract Pharmacogenetics can enhance cardiovascular disease (CVD) treatment by tailoring drug therapy to genetic profiles and minimising trial-and-error approaches. Genetic variability influences responses to common CVD drugs, including antiplatelet drugs (clopidogrel and aspirin), anticoagulants (...

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Main Authors: Ayat Shorbaji, Peter Natesan Pushparaj, Ayat B. Al-Ghafari, Loubna Siraj Mira, Mohammad Abdullah Basabrain, Muhammad Imran Naseer, Farid Ahmed, Muhammad Abu-Elmagd, Mahmood Rasool, Sherin Bakhashab
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:npj Genomic Medicine
Online Access:https://doi.org/10.1038/s41525-025-00511-6
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https://doi.org/10.1038/s41525-025-00511-6

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