Link N Directly Targets IL-1β to Suppress Inflammation and Regulate Sensory Pain in Intervertebral Disc Degeneration

Link N Directly Targets IL-1β to Suppress Inflammation and Regulate Sensory Pain in Intervertebral Disc Degeneration

Intervertebral disc (IVD) disease is typically characterized by the degradation of IVD tissue, secretion of inflammatory and painful factors, and hyperinnervation of the disc. The pro-inflammatory cytokine interleukin-1β (IL-1β) has been regarded as a principal factor in orchestrating disc degenerat...

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Bibliographic Details
Main Authors: Michael P. Grant, Muskan Alad, Fajer Yousef, Laura M. Epure, John Antoniou, Fackson Mwale
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Biomolecules
Subjects:
intervertebral disc
degeneration
back pain
link N
interleukin-1β
inflammation
Online Access:https://www.mdpi.com/2218-273X/15/4/603
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