miR-155 induces sepsis-associated damage to the intestinal mucosal barrier via sirtuin 1/nuclear factor-κB-mediated intestinal pyroptosis

miR-155 induces sepsis-associated damage to the intestinal mucosal barrier via sirtuin 1/nuclear factor-κB-mediated intestinal pyroptosis

Sepsis is a life-threatening state of organ dysfunction caused by systemic inflammation and a dysfunctional response to host infections that can induce severe intestinal mucosal damage. Pyroptosis is mediated by the activated NOD-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome af...

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Bibliographic Details
Main Authors: Li Zhihua, Wang Yi, Huang Weiwei, Shi Xingyu, Ma Tao, Yu Xiangyou
Format: Article
Language:English
Published: China Science Publishing & Media Ltd. 2024-09-01
Series:Acta Biochimica et Biophysica Sinica
Subjects:
intestinal barrier dysfunction
miR-155
NF-κB
pyroptosis
sepsis
SIRT1
Online Access:https://www.sciengine.com/doi/10.3724/abbs.2024124
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https://www.sciengine.com/doi/10.3724/abbs.2024124

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