Repurposing Cyclic Guanosine Monophosphate Pathway Medications, from Vasodilation toward Changing the Face of Heart Failure

Repurposing Cyclic Guanosine Monophosphate Pathway Medications, from Vasodilation toward Changing the Face of Heart Failure

Advanced heart failure (HF) is characterized by repeated hospital admissions due to recurring need for intravenous inotropes. Among the most commonly used medications used in this context, is milrinone, which increases the myocardial relaxation velocity, what is known as lusitropy. This effect is me...

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Bibliographic Details
Main Authors: Antoine Fakhry AbdelMassih, Buthaina Ramadan, Jana Tarek ElDemerdash, Monia Mostafa Zayed, M. Wasim Soued, Nadine El-Husseiny, Yousef M. Husseiny, Passant Saad
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-10-01
Series:Heart Views
Subjects:
cyclic guanosine monophosphate-dependent kinases
lusitropy
milrinone
vericiguat
Online Access:https://journals.lww.com/10.4103/heartviews.heartviews_122_24
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https://journals.lww.com/10.4103/heartviews.heartviews_122_24

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