Identification of angiotensin II-responsive circadian clock gene expression in adrenal zona glomerulosa cells and human adrenocortical H295R cells

Identification of angiotensin II-responsive circadian clock gene expression in adrenal zona glomerulosa cells and human adrenocortical H295R cells

The mammalian circadian timing system is organized in a hierarchy, with the master clock residing in the suprachiasmatic nucleus (SCN) of the hypothalamus and subsidiary peripheral clocks in peripheral tissues. Because of the diversity of peripheral tissues and cell-types in the body, the existence...

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Bibliographic Details
Main Authors: Tomohiro Otani, Takahito Miyake, Takumi Ota, Daisuke Yarimizu, Yuuki Nakagawa, Iori Murai, Hitoshi Okamura, Emi Hasegawa, Masao Doi
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Endocrinology
Subjects:
chronobiology
circadian rhythm
zona glomerulosa
angiotensin II
candesartan
chronotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2025.1525844/full
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https://www.frontiersin.org/articles/10.3389/fendo.2025.1525844/full

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