Superior outcome of labial mucosal autograft over limbal allograft in the management of recurrent pterygium with symblepharon: a case report
A 40-year-old woman visited our clinic for recurred pterygium and symblepharon in the right eye. She had a history of pterygium excision 8 years before. Over the course of 7 years, we performed pterygium excision combined initially with mitomycin C (MMC) application and conjunctival autograft. This...
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Frontiers Media S.A.
2024-10-01
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| Series: | Frontiers in Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2024.1452579/full |
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| author | Joo Youn Oh Joo Youn Oh Sang In Khwarg |
| author_facet | Joo Youn Oh Joo Youn Oh Sang In Khwarg |
| author_sort | Joo Youn Oh |
| collection | DOAJ |
| description | A 40-year-old woman visited our clinic for recurred pterygium and symblepharon in the right eye. She had a history of pterygium excision 8 years before. Over the course of 7 years, we performed pterygium excision combined initially with mitomycin C (MMC) application and conjunctival autograft. This was followed by three procedures using limbal allografts, MMC application, and amniotic membrane transplantation. All procedures were unsuccessful, resulting in aggressive recurrences of pterygial mass and symblepharon, extraocular movement limitation, corneal astigmatism, and decreased visual acuity. Ultimately, we applied a labial mucosal autograft after the recession of pterygial tissue. No complications were observed. Two and a half years postoperatively, the labial mucosal autograft was well-integrated into the conjunctival surface without symblepharon recurrence or abduction limitation. Corneal clarity was restored, and astigmatism was reduced, with no recurrence of pterygium. In conclusion, a labial mucosal autograft is a viable treatment option in complex cases of recalcitrantly recurrent pterygium with symblepharon. |
| format | Article |
| id | doaj-art-c0495b7f47fb45ed8ef4e8466519f310 |
| institution | OA Journals |
| issn | 2296-858X |
| language | English |
| publishDate | 2024-10-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj-art-c0495b7f47fb45ed8ef4e8466519f3102025-08-20T02:09:55ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2024-10-011110.3389/fmed.2024.14525791452579Superior outcome of labial mucosal autograft over limbal allograft in the management of recurrent pterygium with symblepharon: a case reportJoo Youn Oh0Joo Youn Oh1Sang In Khwarg2Laboratory of Ocular Regenerative Medicine and Immunology, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of KoreaDepartment of Ophthalmology, Seoul National University College of Medicine, Seoul, Republic of KoreaDepartment of Ophthalmology, Seoul National University College of Medicine, Seoul, Republic of KoreaA 40-year-old woman visited our clinic for recurred pterygium and symblepharon in the right eye. She had a history of pterygium excision 8 years before. Over the course of 7 years, we performed pterygium excision combined initially with mitomycin C (MMC) application and conjunctival autograft. This was followed by three procedures using limbal allografts, MMC application, and amniotic membrane transplantation. All procedures were unsuccessful, resulting in aggressive recurrences of pterygial mass and symblepharon, extraocular movement limitation, corneal astigmatism, and decreased visual acuity. Ultimately, we applied a labial mucosal autograft after the recession of pterygial tissue. No complications were observed. Two and a half years postoperatively, the labial mucosal autograft was well-integrated into the conjunctival surface without symblepharon recurrence or abduction limitation. Corneal clarity was restored, and astigmatism was reduced, with no recurrence of pterygium. In conclusion, a labial mucosal autograft is a viable treatment option in complex cases of recalcitrantly recurrent pterygium with symblepharon.https://www.frontiersin.org/articles/10.3389/fmed.2024.1452579/fulllabial mucosal autograftlimbal allograftoral mucosal graftpterygiumsymblepharon |
| spellingShingle | Joo Youn Oh Joo Youn Oh Sang In Khwarg Superior outcome of labial mucosal autograft over limbal allograft in the management of recurrent pterygium with symblepharon: a case report Frontiers in Medicine labial mucosal autograft limbal allograft oral mucosal graft pterygium symblepharon |
| title | Superior outcome of labial mucosal autograft over limbal allograft in the management of recurrent pterygium with symblepharon: a case report |
| title_full | Superior outcome of labial mucosal autograft over limbal allograft in the management of recurrent pterygium with symblepharon: a case report |
| title_fullStr | Superior outcome of labial mucosal autograft over limbal allograft in the management of recurrent pterygium with symblepharon: a case report |
| title_full_unstemmed | Superior outcome of labial mucosal autograft over limbal allograft in the management of recurrent pterygium with symblepharon: a case report |
| title_short | Superior outcome of labial mucosal autograft over limbal allograft in the management of recurrent pterygium with symblepharon: a case report |
| title_sort | superior outcome of labial mucosal autograft over limbal allograft in the management of recurrent pterygium with symblepharon a case report |
| topic | labial mucosal autograft limbal allograft oral mucosal graft pterygium symblepharon |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2024.1452579/full |
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