Metformin inhibits the IL-6-induced epithelial-mesenchymal transition and lung adenocarcinoma growth and metastasis.

Metformin inhibits the IL-6-induced epithelial-mesenchymal transition and lung adenocarcinoma growth and metastasis.

<h4>Objective</h4>Epithelial-mesenchymal transition (EMT) plays an important role in cancer tumorigenesis. However, the underlying mechanisms of EMT in lung adenocarcinoma, and how this process might be inhibited, remain to be explored. This study investigated the role of IL-6 in lung ad...

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Main Authors: Zhongquan Zhao, Xiaoming Cheng, Yubo Wang, Rui Han, Li Li, Tong Xiang, Luhang He, Haixia Long, Bo Zhu, Yong He
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0095884&type=printable
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0095884&type=printable

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