The Diagnostic Values of Ischemia-Modified Albumin in Patients with Acute Abdominal Pain and Its Role in Differentiating Acute Abdomen

Aim. The aim of this study was to evaluate the diagnostic value of serum ischemia-modified albumin (IMA) levels in patients presenting to the emergency department with acute abdominal pain and its use in differentiating acute surgical abdomen. Methods. This single-center prospective cross-sectional...

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Main Authors: Selman Yeniocak, Fatma Saraç, Mustafa Yazıcıoğlu, Nadiye Karabulut, Akın Ünal, Esma Yücetaş, Macit Koldaş, İbrahim Akkoç, Mustafa Ekici, Togay Evrin
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Emergency Medicine International
Online Access:http://dx.doi.org/10.1155/2020/7925975
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author Selman Yeniocak
Fatma Saraç
Mustafa Yazıcıoğlu
Nadiye Karabulut
Akın Ünal
Esma Yücetaş
Macit Koldaş
İbrahim Akkoç
Mustafa Ekici
Togay Evrin
author_facet Selman Yeniocak
Fatma Saraç
Mustafa Yazıcıoğlu
Nadiye Karabulut
Akın Ünal
Esma Yücetaş
Macit Koldaş
İbrahim Akkoç
Mustafa Ekici
Togay Evrin
author_sort Selman Yeniocak
collection DOAJ
description Aim. The aim of this study was to evaluate the diagnostic value of serum ischemia-modified albumin (IMA) levels in patients presenting to the emergency department with acute abdominal pain and its use in differentiating acute surgical abdomen. Methods. This single-center prospective cross-sectional study included 334 adult patients who presented to the emergency department. These consisted of 194 patients (Group 1) with nontraumatic abdominal pain commencing in the preceding week, who were definitely diagnosed and either hospitalized in a specific department or planned for discharge, and a control group of 140 patients (Group 2). Results. The mean IMA value of the patients diagnosed with acute appendicitis was statistically significantly higher than that of the control group. The mean IMA value of the patients diagnosed with acute appendicitis, ovarian pathologies, and gastritis-peptic ulcer was statistically significantly higher than that of the nonspecific abdominal pain group. Conclusion. Serum IMA levels can be used as a diagnostic marker in patients with acute appendicitis. Furthermore, serum IMA levels in patients presenting to the emergency department with abdominal pain may be indicative of patients requiring surgery or of complicated cases, particularly in terms of acute appendicitis and ovarian pathologies.
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spelling doaj-art-c039f864189445cda9c376b7a20b1b722025-02-03T06:46:36ZengWileyEmergency Medicine International2090-28402090-28592020-01-01202010.1155/2020/79259757925975The Diagnostic Values of Ischemia-Modified Albumin in Patients with Acute Abdominal Pain and Its Role in Differentiating Acute AbdomenSelman Yeniocak0Fatma Saraç1Mustafa Yazıcıoğlu2Nadiye Karabulut3Akın Ünal4Esma Yücetaş5Macit Koldaş6İbrahim Akkoç7Mustafa Ekici8Togay Evrin9University of Health Sciences, Haseki Training and Research Hospital, Emergency Department, Istanbul, TurkeyUniversity of Health Sciences, Haseki Training and Research Hospital, Clinic of Pediatric Surgery, Istanbul, TurkeyUniversity of Health Sciences, Bakırköy Sadi Konuk Training and Research Hospital, Emergency Department, Istanbul, TurkeyUniversity of Health Sciences, Haseki Training and Research Hospital, Family Medicine Department, Istanbul, TurkeyUniversity of Health Sciences, Haseki Training and Research Hospital, Clinic of Surgery, Istanbul, TurkeyUniversity of Health Sciences, Haseki Training and Research Hospital, Clinic of Clinical Chemistry, Istanbul, TurkeyUniversity of Health Sciences, Haseki Training and Research Hospital, Clinic of Clinical Chemistry, Istanbul, TurkeyUniversity of Health Sciences, Haseki Training and Research Hospital, Department of Anesthesia and Reanimation, Istanbul, TurkeyUfuk University Faculty of Medicine, Department of Emergency Medicine, Ankara, TurkeyKilis State Hospital, Emergency Room, Kilis, TurkeyAim. The aim of this study was to evaluate the diagnostic value of serum ischemia-modified albumin (IMA) levels in patients presenting to the emergency department with acute abdominal pain and its use in differentiating acute surgical abdomen. Methods. This single-center prospective cross-sectional study included 334 adult patients who presented to the emergency department. These consisted of 194 patients (Group 1) with nontraumatic abdominal pain commencing in the preceding week, who were definitely diagnosed and either hospitalized in a specific department or planned for discharge, and a control group of 140 patients (Group 2). Results. The mean IMA value of the patients diagnosed with acute appendicitis was statistically significantly higher than that of the control group. The mean IMA value of the patients diagnosed with acute appendicitis, ovarian pathologies, and gastritis-peptic ulcer was statistically significantly higher than that of the nonspecific abdominal pain group. Conclusion. Serum IMA levels can be used as a diagnostic marker in patients with acute appendicitis. Furthermore, serum IMA levels in patients presenting to the emergency department with abdominal pain may be indicative of patients requiring surgery or of complicated cases, particularly in terms of acute appendicitis and ovarian pathologies.http://dx.doi.org/10.1155/2020/7925975
spellingShingle Selman Yeniocak
Fatma Saraç
Mustafa Yazıcıoğlu
Nadiye Karabulut
Akın Ünal
Esma Yücetaş
Macit Koldaş
İbrahim Akkoç
Mustafa Ekici
Togay Evrin
The Diagnostic Values of Ischemia-Modified Albumin in Patients with Acute Abdominal Pain and Its Role in Differentiating Acute Abdomen
Emergency Medicine International
title The Diagnostic Values of Ischemia-Modified Albumin in Patients with Acute Abdominal Pain and Its Role in Differentiating Acute Abdomen
title_full The Diagnostic Values of Ischemia-Modified Albumin in Patients with Acute Abdominal Pain and Its Role in Differentiating Acute Abdomen
title_fullStr The Diagnostic Values of Ischemia-Modified Albumin in Patients with Acute Abdominal Pain and Its Role in Differentiating Acute Abdomen
title_full_unstemmed The Diagnostic Values of Ischemia-Modified Albumin in Patients with Acute Abdominal Pain and Its Role in Differentiating Acute Abdomen
title_short The Diagnostic Values of Ischemia-Modified Albumin in Patients with Acute Abdominal Pain and Its Role in Differentiating Acute Abdomen
title_sort diagnostic values of ischemia modified albumin in patients with acute abdominal pain and its role in differentiating acute abdomen
url http://dx.doi.org/10.1155/2020/7925975
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