Butyrate enhances gut dysbiosis by activating the cAMP/PKA/CREB signaling pathway to inhibit the progression of endometrial carcinoma

Butyrate enhances gut dysbiosis by activating the cAMP/PKA/CREB signaling pathway to inhibit the progression of endometrial carcinoma

Abstract Background Gut microbiota may contribute to the progression and prognosis of extra-intestinal tumors. The relationship and mechanism between endometrial carcinoma (EC), the gut microbiota, and short-chain fatty acids (SCFAs) remain ambiguous. This study aimed to ascertain whether alteration...

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Bibliographic Details
Main Authors: Muheng Tao, Tingting Wu, Xin Zhou, Fengjie Li, Yingfan Chen, Kaijian Ling, Zhiqing Liang
Format: Article
Language:English
Published: BMC 2025-08-01
Series:BMC Microbiology
Subjects:
Endometrial carcinoma
Gut microbiota
Fecal microbiota transplantation
Short-chain fatty acids
Online Access:https://doi.org/10.1186/s12866-025-04190-2
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https://doi.org/10.1186/s12866-025-04190-2

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