Head to head comparison of two PET/CT imaging agents, [18F]D3FSP ([18F]P16-129) and [18F]AV45, in patients with alzheimer’s disease

Abstract Background A new β-amyloid (Aβ) targeting radiotracer, [18F]D3FSP ([18F]P16-129), for diagnosis of Alzheimer’s disease (AD) is reported. This radiotracer is a deuterated N-methyl derivative of Amyvid (AV-45, florbetapir f18) which was FDA-approved in 2013. Deuteration may alter a tracer’s P...

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Bibliographic Details
Main Authors: David Alexoff, Dean F. Wong, Hiroto Kuwabara, Robert F. Dannals, Karl Ploessl, Hank F. Kung
Format: Article
Language:English
Published: SpringerOpen 2025-06-01
Series:EJNMMI Research
Subjects:
Online Access:https://doi.org/10.1186/s13550-025-01276-w
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