Exploration of biomarkers for inhibitor development in persons with hemophilia A

Exploration of biomarkers for inhibitor development in persons with hemophilia A

Background: Inhibitor development remains a significant challenge for hemophilia A (HA) treatment. Cytokines and glycosylation play crucial roles in inducing and regulating immune responses. Cytokine and altered N-glycan profiles have the potential to be biomarkers in association with the presence o...

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Main Authors: Meng-Ni Fan, Tangliang Shen, Barbara A. Konkle, Xiaohe Cai, Ting-Yen Chao, Marilyn Manco-Johnson, Anna V. Faino, Junping Zhang, Shumin Bao, Weidong Xiao, Lei Li, Carol H. Miao
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Research and Practice in Thrombosis and Haemostasis
Subjects:
biomarker
cytokine
glycosylation
hemophilia A
inhibitors
Online Access:http://www.sciencedirect.com/science/article/pii/S2475037925002018
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