TP53-dependence on the effect of doxorubicin and Src inhibitor combination therapy

The anticancer effects of Src kinase inhibitors are controversial. This study found an association between alterations in the TP53 gene and the synergy score for combination treatment with doxorubicin and an Src kinase inhibitor using human osteosarcoma cell lines (MG63 and U2OS) and human colon can...

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Bibliographic Details
Main Authors: Yun Sun Lee, Ji-Yoon Choi, Jeeyun Lee, Da Mi Shim, Jaesoo Kim, Woong-Yang Park, Do-Hyun Nam, Sung Wook Seo
Format: Article
Language:English
Published: SAGE Publishing 2018-08-01
Series:Tumor Biology
Online Access:https://doi.org/10.1177/1010428318794217
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