Astrocytic lipid droplets contain MHCII and may act as cogs in the antigen presentation machinery

Abstract Lipid droplets (LDs) are crucial for energy homeostasis, but are also involved in a wide spectrum of other cellular processes. Accumulating data identifies LDs as an important player in inflammation. However, the underlying mechanisms and the impact of LDs on neuroinflammation remain unclea...

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Bibliographic Details
Main Authors: Chiara Beretta, Abdulkhalek Dakhel, Khalid Eltom, Fredrik Rosqvist, Simon Uzoni, Tobias Mothes, John S. Fletcher, Ulf Risérus, Dag Sehlin, Jinar Rostami, Wojciech Piotr Michno, Anna Erlandsson
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Journal of Neuroinflammation
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Online Access:https://doi.org/10.1186/s12974-025-03452-0
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