Identification of relevant analytical methods for adeno-associated virus stability assessment during formulation development

ABSTRACT Formulation development for gene therapy viral vectors requires high-performance analytical methods that indicate or predict virus stability. Additionally, if testing involves multiple excipients, sample throughput must be sufficiently high, and the method should require low amounts of viru...

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Bibliographic Details
Main Authors: Carina Rodenstein, Eva Schmid, Natalia Markova, Andreas Seidl
Format: Article
Language:English
Published: American Society for Microbiology 2025-08-01
Series:Microbiology Spectrum
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Online Access:https://journals.asm.org/doi/10.1128/spectrum.01806-24
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