Identification and characterization of the host protein DNAJC14 as a broadly active flavivirus replication modulator.

Viruses in the Flavivirus genus of the Flaviviridae family are arthropod-transmitted and contribute to staggering numbers of human infections and significant deaths annually across the globe. To identify cellular factors with antiviral activity against flaviviruses, we screened a cDNA library using...

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Bibliographic Details
Main Authors: Zhigang Yi, Lindsey Sperzel, Cindy Nürnberger, Peter J Bredenbeek, Kirk J Lubick, Sonja M Best, Cristina T Stoyanov, Lok Man J Law, Zhenghong Yuan, Charles M Rice, Margaret R MacDonald
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1001255&type=printable
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