Application of RNAi to Genomic Drug Target Validation in Schistosomes.

Concerns over the possibility of resistance developing to praziquantel (PZQ), has stimulated efforts to develop new drugs for schistosomiasis. In addition to the development of improved whole organism screens, the success of RNA interference (RNAi) in schistosomes offers great promise for the identi...

Full description

Saved in:
Bibliographic Details
Main Authors: Alessandra Guidi, Nuha R Mansour, Ross A Paveley, Ian M Carruthers, Jérémy Besnard, Andrew L Hopkins, Ian H Gilbert, Quentin D Bickle
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-05-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0003801
Tags: Add Tag
No Tags, Be the first to tag this record!