Bacillus megaterium has both a functional BluB protein required for DMB synthesis and a related flavoprotein that forms a stable radical species.
Despite the extensive study of the biosynthesis of the complex molecule B12 (cobalamin), the mechanism by which the lower ligand 5,6-dimethylbenzimidazole (DMB) is formed has remained something of a mystery. However, recent work has identified and characterized a DMB-synthase (BluB) responsible for...
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| Main Authors: | Hannah F Collins, Rebekka Biedendieck, Helen K Leech, Michael Gray, Jorge C Escalante-Semerena, Kirsty J McLean, Andrew W Munro, Stephen E J Rigby, Martin J Warren, Andrew D Lawrence |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2013-01-01
|
| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0055708 |
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