Bacillus megaterium has both a functional BluB protein required for DMB synthesis and a related flavoprotein that forms a stable radical species.

Bacillus megaterium has both a functional BluB protein required for DMB synthesis and a related flavoprotein that forms a stable radical species.

Despite the extensive study of the biosynthesis of the complex molecule B12 (cobalamin), the mechanism by which the lower ligand 5,6-dimethylbenzimidazole (DMB) is formed has remained something of a mystery. However, recent work has identified and characterized a DMB-synthase (BluB) responsible for...

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Bibliographic Details
Main Authors: Hannah F Collins, Rebekka Biedendieck, Helen K Leech, Michael Gray, Jorge C Escalante-Semerena, Kirsty J McLean, Andrew W Munro, Stephen E J Rigby, Martin J Warren, Andrew D Lawrence
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0055708
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https://doi.org/10.1371/journal.pone.0055708

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