Preclinical Validation of MIN-T: A Novel Controlled-Released Formulation for the Adjunctive Local Application of Minocycline in Periodontitis

Preclinical Validation of MIN-T: A Novel Controlled-Released Formulation for the Adjunctive Local Application of Minocycline in Periodontitis

<b>Background:</b> Adjunctive treatment of periodontitis lacks solutions which allow for enough time for wound healing in the periodontal pockets by avoiding fast re-colonization. Such a solution might be an antibiotic-containing formulation with a controlled release over a period of wee...

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Main Authors: Małgorzata Benedyk-Machaczka, Piotr Mydel, Karsten Mäder, Marta Kaminska, Nadine Taudte, Marcel Naumann, Martin Kleinschmidt, Sandra Sarembe, Andreas Kiesow, Sigrun Eick, Mirko Buchholz
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Antibiotics
Subjects:
periodontitis
proof-of-concept
adjunctive therapy
minocycline
local application
controlled release
Online Access:https://www.mdpi.com/2079-6382/13/11/1012
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