cDNA library construction from a small amount of RNA: adaptor-ligation approach for two-round cRNA amplification using T7 and SP6 RNA polymerases

In this study, we developed a method that allows cDNA library construction from a small amount of RNA without causing serious size bias in the resulting cDNA population. For this purpose, we adopted two-round cRNA amplification by T7 and SP6 RNA polymerases. The first-round cDNAs, flanked by the pro...

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Bibliographic Details
Main Authors: Reiko Ohara, Reiko F. Kikuno, Hiroshi Kitamura, Osamu Ohara
Format: Article
Language:English
Published: Taylor & Francis Group 2005-03-01
Series:BioTechniques
Online Access:https://www.future-science.com/doi/10.2144/05383RR01
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