Variation in Immune and Inflammatory Blood Markers in Advanced Melanoma Patients Treated with PD-1 Inhibitors: A Preliminary Exploratory Study

Variation in Immune and Inflammatory Blood Markers in Advanced Melanoma Patients Treated with PD-1 Inhibitors: A Preliminary Exploratory Study

<b>Background:</b> Immune checkpoint inhibitors (ICIs) used for the treatment of advanced melanoma have yielded significant results, with long-term responses and improved survival rates, but not for all treated patients. Therefore, predictive biomarkers of response to ICI therapy have be...

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Main Authors: Lucica Madalina Bolovan, Marieta Elena Panait, Antonela Busca, Adina Elena Stanciu, Daniela Chiriac, Corina Elena Mihalcea, Camelia Mia Hotnog, Mihai Teodor Georgescu, Silviu Cristian Voinea, Virgiliu Mihail Prunoiu, Lorelei Irina Brasoveanu, Laurentia Nicoleta Gales
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Biomedicines
Subjects:
advanced melanoma
PD-1 inhibitors
peripheral blood immune cells
inflammatory markers
predictive melanoma biomarkers
cytokines
Online Access:https://www.mdpi.com/2227-9059/13/6/1378
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