Genome‐scale gene/reaction essentiality and synthetic lethality analysis
Abstract Synthetic lethals are to pairs of non‐essential genes whose simultaneous deletion prohibits growth. One can extend the concept of synthetic lethality by considering gene groups of increasing size where only the simultaneous elimination of all genes is lethal, whereas individual gene deletio...
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| Main Authors: | Patrick F Suthers, Alireza Zomorrodi, Costas D Maranas |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer Nature
2009-08-01
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| Series: | Molecular Systems Biology |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/msb.2009.56 |
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