Posterior iliac crest vs. proximal tibia: distinct sources of anti-inflammatory and regenerative cells with comparable 6-month clinical outcomes in treatment of osteoarthritis

Posterior iliac crest vs. proximal tibia: distinct sources of anti-inflammatory and regenerative cells with comparable 6-month clinical outcomes in treatment of osteoarthritis

Abstract Background Human bone marrow is a source of mesenchymal stem cells (MSCs), other progenitor cells, and factors with anti-inflammatory and regenerative capacity. Though the fraction of MSCs out of the nucleated cells is very small, bone marrow aspirate (BMA) for osteoarthritis (OA) has notew...

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Main Authors: E. Mormone, L. Savastano, G. Rossi, F. Maruccia, G. Di Maggio, N. P. Sinisi, M. Sandri, M. Copetti, E. De Santis, V. Guerra, G. Biancofiore, C. Cisternino, E. Caradonna, P. Graziano, F. L. Gorgoglione
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Journal of Translational Medicine
Online Access:https://doi.org/10.1186/s12967-024-05924-y
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https://doi.org/10.1186/s12967-024-05924-y

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