Systems genetics uncovers associations among host amylase locus, gut microbiome, and metabolic traits in mice

Systems genetics uncovers associations among host amylase locus, gut microbiome, and metabolic traits in mice

Abstract Background Population studies have revealed associations between host genetic and gut microbiome in humans and mice. However, the molecular bases for how host genetic variation impacts the gut microbial community and bacterial metabolic niches remain largely unknown. Results We leveraged 90...

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Bibliographic Details
Main Authors: Qijun Zhang, Evan R. Hutchison, Calvin Pan, Matthew F. Warren, Mark P. Keller, Alan D. Attie, Aldons J. Lusis, Federico E. Rey
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Microbiome
Subjects:
Systems genetics
Gut microbiome
Genetic association study
Metagenomics
Hybrid mouse diversity panel
Online Access:https://doi.org/10.1186/s40168-025-02093-y
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https://doi.org/10.1186/s40168-025-02093-y

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