Mechanistic studies of Ca2+-induced classical pyroptosis pathway promoting renal adhesion on calcium oxalate kidney stone formation

Abstract This study aims to investigate the role of hypercalciuria and pyroptosis in the formation of calcium oxalate kidney stones. Bioinformatics analysis was performed to compare the correlation of pyroptosis scores and cell adhesion scores between Randall’s plaques and normal tissues from kidney...

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Bibliographic Details
Main Authors: Jinjie Xiang, Maoxin Lv, Yuhui Luo, Kunbin Ke, Baiyu Zhang, Mengyue Wang, Kun Zhang, Hao Li
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-91460-8
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