Leveraging diverse liquid–liquid phase separation patterns to predict the prognosis and immunotherapy of pediatric acute myeloid leukemia

Leveraging diverse liquid–liquid phase separation patterns to predict the prognosis and immunotherapy of pediatric acute myeloid leukemia

Abstract Background Despite improvements in 5-year survival rates for pediatric acute myeloid leukemia (P-AML) over recent decades, the relapse rate remains high. This challenge is compounded by the absence of reliable prognostic biomarkers, which limits the effectiveness of predictive, preventive,...

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Bibliographic Details
Main Authors: Min Kong, Yezhen Yang, Zhixiang Wu, Ying Li, Zhijuan Kang, Qin Zhao, Huan Chang, Zuocheng Yang
Format: Article
Language:English
Published: BMC 2025-08-01
Series:BMC Cancer
Subjects:
Pediatric acute myeloid leukemia
Liquid-liquid phase separation
Prognosis
Immunotherapy efficacy
Immune infiltration
Online Access:https://doi.org/10.1186/s12885-025-14718-4
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https://doi.org/10.1186/s12885-025-14718-4

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