Utility of Serum Biomarkers of Myocardial Fibrosis in High-Gradient Severe Aortic Stenosis: An Explorative Cardiovascular Magnetic Resonance Imaging-Based Study

Utility of Serum Biomarkers of Myocardial Fibrosis in High-Gradient Severe Aortic Stenosis: An Explorative Cardiovascular Magnetic Resonance Imaging-Based Study

<b>Background:</b> Myocardial fibrosis in aortic stenosis (AS) is associated with a significant risk of poor clinical outcomes. Myocardial fibrosis can be evaluated using cardiovascular magnetic resonance (CMR) imaging and may be useful for risk-stratifying patients at high risk for poor...

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Bibliographic Details
Main Authors: Megan R. Rajah, Erna Marais, Gerald J. Maarman, Emma Doubell, Anton F. Doubell, Philip G. Herbst
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Diagnostics
Subjects:
myocardial fibrosis
biomarkers
transforming growth factor-beta 1
collagen synthesis
aortic stenosis
cardiovascular magnetic resonance imaging
Online Access:https://www.mdpi.com/2075-4418/15/9/1143
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