Exosomes from high-altitude cerebral edema patients induce cognitive dysfunction by altering oxidative stress responses in mice

Exosomes from high-altitude cerebral edema patients induce cognitive dysfunction by altering oxidative stress responses in mice

Abstract The impact of exosomes derived from patients with High Altitude Cerebral Edema (HACE) on cognitive function in mice was investigated, along with the underlying mechanisms. Exosomes were extracted from HACE patients and injected into the dentate gyrus (DG) of mice. A series of behavioral tes...

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Main Authors: Qiang Fu, Rui Qiu, Quan Tang, Xiaodong Li, Yaobo Li, Yuxiang Qin, Qiaosheng Li, Jia Yao, Zhongyong Jiang, Huan Xu, Yong Cheng
Format: Article
Language:English
Published: Nature Publishing Group 2025-07-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-025-03469-2
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https://doi.org/10.1038/s41398-025-03469-2

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