Clinical and genetic characteristics of acute myeloid leukemia with t(8;21) in children and results of therapy according to protocol AML-MM-2000

Clinical and genetic characteristics of acute myeloid leukemia with t(8;21) in children and results of therapy according to protocol AML-MM-2000

A t(8;21) is the most frequent abnormality in AML in children. Patients with this genetic abnormality are traditionally expected favorable prognosis with a probability of cure up to 80 %. Known additional cytogenetic abnormalities in AML with t(8;21) not affecting prognosis. These include loss of on...

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Main Authors: I. I. Kalinina, M. M. Shneyder, N. P. Kirsanova, D. D. Baydildina, E. V. Suntsova, O. V. Goronkova, L. A. Khachatryan, G. A. Novichkova, M. A. Maschan, R. I. Yutskevich, E. V. Volochnik, T. V. Savitskaya, N. V. Minakovskaya, I. V. Proleskovskaya, I. V. Emelyanova, O. V. Karas, N. V. Migal, Yu. E. Mareyko, A. G. Drekov, J. V. Rumyantseva, E. V. Fleyshman, T. V. Nasedkina, O. V. Aleynikova, A. A. Maschan
Format: Article
Language:Russian
Published: ABV-press 2014-07-01
Series:Онкогематология
Subjects:
children
acute myeloid leukemia
t(8
21)
aml-mm-2000 protocol
Online Access:https://oncohematology.abvpress.ru/ongm/article/view/100
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