Characteristics of SARS-CoV-2-associated severe episodes of monoclonal gammopathy-associated capillary leak syndrome (Clarkson disease)

Characteristics of SARS-CoV-2-associated severe episodes of monoclonal gammopathy-associated capillary leak syndrome (Clarkson disease)

Abstract Background Monoclonal gammopathy-associated capillary leak syndrome (MG-CLS) is a rare condition characterized by recurrent episodes of hypovolemic shock caused by a sudden increase in capillary permeability. The COVID-19 pandemic has been associated with a rise in MG-CLS episodes and incre...

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Main Authors: Nissim Grinberg, Maddalena Alessandra Wu, Quentin Moyon, Sybille Merceron, Yannick Fedun, Marie Gousseff, Romain Sonneville, François Lhote, Elie Azoulay, Jean-Herlé Raphalen, David Saadoun, Ygal Benhamou, Jean-Paul Mira, Guillaume Dumas, Pierre Bay, Jérôme Devaquet, Laurent Argaud, Marc Lambert, Avinash Aujayeb, Basile Henriot, Amandine Bichon, Thomas Bocar, John Harty, Remo Melchio, Franck Leibinger, Laure Calvet, Tomas Urbina, Laurent Bodson, Jean-Marie Tonnelier, Danielle Reuter, Emmanuel Canet, Gilles Blaison, Julien Maizel, Nicholas Sedillot, Laurence Dangers, Vincent Eble, Franco Verlicchi, Stanislas Faguer, Jonathan Montomoli, Geoffroy Dingemans, Marc Mikulski, Jonas Pochard, Fabrice Uhel, Fleur Cohen-Aubart, Charles-Edouard Luyt, Alexis Mathian, Alain Combes, Riccardo Colombo, Zahir Amoura, Marc Pineton de Chambrun, the EurêClark Study Group
Format: Article
Language:English
Published: SpringerOpen 2025-05-01
Series:Annals of Intensive Care
Subjects:
Monoclonal gammopathy-associated capillary-leak syndrome
Monoclonal gammopathy
Clarkson disease
SARS-CoV-2
Intensive care unit
Online Access:https://doi.org/10.1186/s13613-025-01483-7
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https://doi.org/10.1186/s13613-025-01483-7

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