Amantadine reduces sepsis-induced brain injury via NLRP3/caspase-1 inflammasome activation

Objective(s): Sepsis, a severe consequence of infection leading to organ failure, incites damage in frequently affected brain tissue through inflammation and oxidative stress. This study aimed to assess the effectiveness of amantadine, an N-methyl-D-aspartate (NMDA) receptor antagonist, in mitigatin...

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Bibliographic Details
Main Authors: Pinar Karabacak, Ahmet Bindal, Mustafa Ozcan, Ilter Ilhan, Muhammet Tepebası, Melih Arlıoglu, Rumeysa Taner, Halil Ascı
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2025-05-01
Series:Iranian Journal of Basic Medical Sciences
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Online Access:https://ijbms.mums.ac.ir/article_25494_daf8f29479e83afcd7e571ec806c7f92.pdf
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