Identification of Novel Progesterone Receptor (PR) Inhibitors (<i>Homo sapiens</i>) from Metabolites of Biotransformation Fungal: A Bioinformatics Approach

Identification of Novel Progesterone Receptor (PR) Inhibitors (<i>Homo sapiens</i>) from Metabolites of Biotransformation Fungal: A Bioinformatics Approach

<b>Background/Objectives</b>: Steroids have demonstrated selective cytotoxic properties against tumor cells. The pro-gesterone receptor (PR) plays a vital role in the proliferation, cell differentiation, and maintenance of female reproductive tissue, and its malfunction can lead to breas...

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Bibliographic Details
Main Authors: Janaína de Araújo E. Dourado, Samuel Q. Lopes, David Esteban Q. Jimenez, Ryan S. Ramos, Irlon M. Ferreira
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Pharmaceuticals
Subjects:
steroids
fungi
ADMET
androstenedione
hydroxyprogesterone
dihydrotestosterone
Online Access:https://www.mdpi.com/1424-8247/18/2/136
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