Glucocorticosteroids and the Risk of NAFLD in Inflammatory Bowel Disease

Each year, the incidence of nonalcoholic fatty liver (NAFLD) disease increases. NAFLD is a chronic disease. One of the most common causes of NAFLD is an inadequate lifestyle, which is characterized by a lack or low physical activity and eating highly processed foods rich in saturated fat and salt an...

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Main Authors: Sara Jarmakiewicz-Czaja, Aneta Sokal, Piotr Pardak, Rafał Filip
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Canadian Journal of Gastroenterology and Hepatology
Online Access:http://dx.doi.org/10.1155/2022/4344905
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author Sara Jarmakiewicz-Czaja
Aneta Sokal
Piotr Pardak
Rafał Filip
author_facet Sara Jarmakiewicz-Czaja
Aneta Sokal
Piotr Pardak
Rafał Filip
author_sort Sara Jarmakiewicz-Czaja
collection DOAJ
description Each year, the incidence of nonalcoholic fatty liver (NAFLD) disease increases. NAFLD is a chronic disease. One of the most common causes of NAFLD is an inadequate lifestyle, which is characterized by a lack or low physical activity and eating highly processed foods rich in saturated fat and salt and containing low amount of fiber. Moreover, disturbances in intestinal microbiome and the use of certain drugs may predispose to NAFLD. NAFLD is an increasingly described disease in patients with inflammatory bowel disease (IBD). Recent data also indicate a frequent coexistence of metabolic syndrome in this group of patients. Certain groups of drugs also increase the risk of developing inflammation, liver fibrosis, and cirrhosis. Particularly important in the development of NAFLD are steroids, which are used in the treatment of many diseases, for example, IBD. NAFLD is one of the most frequent parenteral manifestations of the disease in IBD patients. However, there is still insufficient information on what dose and exposure time of selected types of steroids may lead to the development of NAFLD. It is necessary to conduct further research in this direction. Therefore, patients with IBD should be constantly monitored for risk factors for the development of NAFLD.
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series Canadian Journal of Gastroenterology and Hepatology
spelling doaj-art-bf2da47c610d4d2592a1451e790b88012025-02-03T05:53:50ZengWileyCanadian Journal of Gastroenterology and Hepatology2291-27972022-01-01202210.1155/2022/4344905Glucocorticosteroids and the Risk of NAFLD in Inflammatory Bowel DiseaseSara Jarmakiewicz-Czaja0Aneta Sokal1Piotr Pardak2Rafał Filip3Institute of Health SciencesInstitute of Health SciencesInstitute of MedicineInstitute of MedicineEach year, the incidence of nonalcoholic fatty liver (NAFLD) disease increases. NAFLD is a chronic disease. One of the most common causes of NAFLD is an inadequate lifestyle, which is characterized by a lack or low physical activity and eating highly processed foods rich in saturated fat and salt and containing low amount of fiber. Moreover, disturbances in intestinal microbiome and the use of certain drugs may predispose to NAFLD. NAFLD is an increasingly described disease in patients with inflammatory bowel disease (IBD). Recent data also indicate a frequent coexistence of metabolic syndrome in this group of patients. Certain groups of drugs also increase the risk of developing inflammation, liver fibrosis, and cirrhosis. Particularly important in the development of NAFLD are steroids, which are used in the treatment of many diseases, for example, IBD. NAFLD is one of the most frequent parenteral manifestations of the disease in IBD patients. However, there is still insufficient information on what dose and exposure time of selected types of steroids may lead to the development of NAFLD. It is necessary to conduct further research in this direction. Therefore, patients with IBD should be constantly monitored for risk factors for the development of NAFLD.http://dx.doi.org/10.1155/2022/4344905
spellingShingle Sara Jarmakiewicz-Czaja
Aneta Sokal
Piotr Pardak
Rafał Filip
Glucocorticosteroids and the Risk of NAFLD in Inflammatory Bowel Disease
Canadian Journal of Gastroenterology and Hepatology
title Glucocorticosteroids and the Risk of NAFLD in Inflammatory Bowel Disease
title_full Glucocorticosteroids and the Risk of NAFLD in Inflammatory Bowel Disease
title_fullStr Glucocorticosteroids and the Risk of NAFLD in Inflammatory Bowel Disease
title_full_unstemmed Glucocorticosteroids and the Risk of NAFLD in Inflammatory Bowel Disease
title_short Glucocorticosteroids and the Risk of NAFLD in Inflammatory Bowel Disease
title_sort glucocorticosteroids and the risk of nafld in inflammatory bowel disease
url http://dx.doi.org/10.1155/2022/4344905
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AT anetasokal glucocorticosteroidsandtheriskofnafldininflammatoryboweldisease
AT piotrpardak glucocorticosteroidsandtheriskofnafldininflammatoryboweldisease
AT rafałfilip glucocorticosteroidsandtheriskofnafldininflammatoryboweldisease