DNA-methylation eraser TET2 activates WTIP expression to suppress an AKT-dependent chemoresistance of gastric cancer

Chemoresistance is one of the major causes of the failure in gastric cancer (GC) treatment and leads to poor clinical outcomes. Ten-eleven translocation (TET) 2 expression and activity are frequently reduced in solid tumors. However, whether TET2 participants in GC chemoresistance remains poorly und...

Full description

Saved in:
Bibliographic Details
Main Authors: Yan Guo, Hongyang Yu, Jinyang Li, Kewei Liu, Mengyi Han, Yuxin Tang, Li Su, Xianfeng Li, Haixia Wu, Dongfeng Chen
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558625000454
Tags: Add Tag
No Tags, Be the first to tag this record!