Identification of novel angiotensin I-converting enzyme inhibitory peptides from walnut (Juglans sigillata Dode) protein hydrolysates and their vascular endothelial protective properties: In silico and in vitro studies

Identification of novel angiotensin I-converting enzyme inhibitory peptides from walnut (Juglans sigillata Dode) protein hydrolysates and their vascular endothelial protective properties: In silico and in vitro studies

The objective of this study was to explore novel functional peptides derived from walnut protein isolate (WPI) that exhibited gastrointestinal stability, angiotensin I-converting enzyme (ACE1) inhibitory activity, and endothelial protective properties. Among the 81 detected peptides, 36 peptides wit...

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Bibliographic Details
Main Authors: Wenyun Xiong, Lixia Guo, Yiting Zhang, Shurui Li, Zihuan Wu, Shengbao Cai
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Current Research in Food Science
Subjects:
Walnut protein isolate
Gastrointestinal digestion
ACE1 inhibitory peptides
Human endothelial cell
Molecular docking
Molecular dynamics simulation
Online Access:http://www.sciencedirect.com/science/article/pii/S2665927125001662
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