Single-cell RNA sequencing reveals palmitoylation-driven cellular heterogeneity and prognostic biomarkers in lung adenocarcinoma

Single-cell RNA sequencing reveals palmitoylation-driven cellular heterogeneity and prognostic biomarkers in lung adenocarcinoma

Background: Lung adenocarcinoma (LUAD) is marked by significant variation within tumor cells and continues to be a major global cause of cancer deaths. Palmitoylation is a dynamic lipid-based modification that occurs after protein synthesis and influences the behavior and lifespan of various cancer-...

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Bibliographic Details
Main Authors: Taibo Huang, Lijie Kou, Qianqian Zhang, Xueya Liu, Xingang Hu
Format: Article
Language:English
Published: Elsevier 2025-11-01
Series:Translational Oncology
Subjects:
Lung adenocarcinoma (LUAD)
Single-cell RNA sequencing (scRNA-seq)
Tumor microenvironment (TME)
Copy number variations (CNVs)
Prognostic biomarkers
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523325002323
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